You probably didn't receive an answer the first time because it's unlikely that there's much we can do to help you. Your issue is not specifically a Twine 2 issue. It's a Windows issue, in general, and an issue with your Windows installation, specifically.
Your best bet to find a solution is likely going to be using a search engine (see: Google, DuckDuckGo, Bing, etc).
Case in point, searching Google for "This app can't run on your PC windows 10" (sans quotes) yielded a plethora of results.
PS: The executable release stores your project data in files within your Documents directory under Twine\Stories, unlike the browser release which only stores them within its own storage. Unless you manually delete those files, you shouldn't have to worry about losing data.