I think it might be better to back up a step and ask what you want the audio to do for your story? I ask because I'm kind of struggling to think of a reason why you'd use a player like that, instead of using the audio tools built-in to SugarCube.
Also, if you are using SugarCube to play your audio, I'd make sure you have the latest version (currently SugarCube v2.28.2), since there were some recent improvements to how SugarCube handles audio. If you need it, you can download the latest version here and the installation instructions are here. Beyond that, I have some audio sample code here, which not only shows how to play audio in Twine, but also explains how to overcome some potential issues you may encounter due to new-ish browser security changes.
Anyways, I'd say that it almost certainly can be done, but you'd be struggling against Twine to do it, rather than using the built-in tools which make it easy, so I'm wondering if there's any good reason why you'd want to do it that way.